The centre of hyperbaric oxygen therapy in Sao Paulo, headed by Machado, MD, has been dealing with treatment of neurological patients since 1979. During the first four years, during the work with patients suffering from neurological disorders caused by ischemia, the doctor together with his colleagues, noticed that the most noticeable and the most universal effect of hyperbaric oxygen therapy (HBOT) is reduction of spasticity. These results, among patients with pareses, have been confirmed by both test results and observations, and their consequence was a significant improval of motor skills.